Research on Amrit Kalash and Angina Pectoris


Indigenous Free Radical Scavenger MAK-4 and MAK-5 in Angina Pectoris. Is it Only a Placebo?

Journal of the Association of Physicians of India, Vol. 42, No. 6, pp. 466-467, 1994.

J. Dogra,* N. Grover,* P. Kumar,* and N. Aneja.**

Conducted at
**Department of Medicine, C.G.H.S., Jaipur, India
**SMS Medical College, Jaipur, India



Thirty patients were evaluated to study the effect of Maharishi Amrit Kalash (MAK4 and MAK5) on angina pectoris. The mean angina frequency per month was 8.87. Twelve lead ECG, computerized TMT and echo studies were done initially, at 6 months, and after 2 years in all cases. Ten grams of MAK-4 paste was given daily in two divided doses, each followed by a MAK5 tablet, for six months. Vasodilator and antihypertensive drugs were continued on ethical grounds. Twenty-four patients (80%) of the total 30 reported a significant improvement after 6 months of therapy. The mean angina frequency per month improved from 8.87 to 3.03 (p<0.001). All patients reported a sense of well-being. Five of 11 hypertensive patients reported a fall in systolic blood pressure. The lipid profile showed a rise in high-density lipoprotein (HDL) which was statistically insignificant. Improved exercise tolerance was observed in 10 cases (33.33%) after 6 months of therapy and this effect was sustained even at 2 years. ECG and echo studies were inconclusive. No side effects or drug interactions were seen. The beneficial effects observed may be the result of the free radical-scavenging property of MAK-4 and MAK-5 on reactive oxygen species (ROS), or an inhibitory effect on lipid peroxidation, or inhibition of platelet aggregation, or all of these in synergism.


Please Note

MAK4 is now called Amrit Kalash Nectar and is only available in New Zealand in sugar-free tablet form as MA7
MAK5 is now called Amrit Kalash Ambrosia.

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